By Application
Roll-Ons
The antiperspirant roll-on is a universally popular dosage form because of ease of production, simple application, economics, and good performance. Customers can choose from several basic formulation types, including clear hydro-alcoholic solutions, oil-in-water emulsions, and anhydrous silicone/ emollient suspensions. Each antiperspirant roll-on formulation exhibits different aesthetic properties which can be tailored to consumer or market preferences.
Two actives are recommended for hydro-alcoholic solutions: Aluminum Chlorohydrex PG (Rehydrol II) and Aluminum Zirconium Pentachlorohydrate 40% solution (Rezal 67). The anhydrous silicone/emollient active suspensions can use any of the actives recommended for sticks in larger particle size grades. Liquids are normally recommended for oil-in-water emulsion roll-ons. A wide range of actives including Aluminum Chlorohydrate, Aluminum Sesquichlorohydrate, and various Aluminum Zirconium actives can all be used depending on sweat reduction performance objectives.
SummitReheis offers the following suggested liquid actives for antiperspirant roll-ons (in decreasing order of expected clinical performance):
| Actives: | Description: |
|---|---|
| UltraZAG | Enhanced Aluminum Zirconium Tetrachlorohydrex gly (45% solution) with optimum zirconium and aluminum polymer distributions and a metals to chloride ratio of 1.15:1 |
| AZG-368/AZG-442 | Aluminum Zirconium Tetrochlorohydrate gly (35%/45% solution) with a metals to chloride ratio of 1.4:1 |
| Reach AZO-956G | Economical Aluminum Octachlorohydrex gly (45% solution) with low zirconium and a metals to chloride ratio of 1.15:1 |
| Rezal 67 | Aluminum Zirconium Pentachlorohydrate (40% solution) with a metals to chloride ratio of 1.75:1 and no glycine |
| Reach 301L | Aluminum sesquichlorohydrate (50% solution) with an aluminum to chloride ratio of 1.65:1 |
| Chlorhydrol 50 | Aluminum Chlorohydrate (50% solution) with an aluminum to chloride ratio of 2.0:1 |
