By Application
Roll-Ons
The antiperspirant roll-on is a universally popular dosage form because of ease of production, simple application, economics, and good performance. Customers can choose from several basic formulation types, including clear hydro-alcoholic solutions, oil-in-water emulsions, and anhydrous silicone/ emollient suspensions. Each antiperspirant roll-on formulation exhibits different aesthetic properties which can be tailored to consumer or market preferences.
An active particularly recommended for hydro-alcoholic solutions is Aluminum Zirconium Pentachlorohydrate 40% solution (Rezal 67). Anhydrous silicone/emollient active suspensions can use any of the actives recommended for sticks in larger particle size grades. Liquids are normally recommended for oil-in-water emulsion roll-ons. A wide range of actives including Aluminum Chlorohydrate, Aluminum Sesquichlorohydrate, and various Aluminum Zirconium actives can all be used depending on sweat reduction performance objectives.
SummitReheis offers the following suggested liquid actives for antiperspirant roll-ons (in increasing order of expected clinical performance):
| Actives: | Description: |
|---|---|
| Chlorhydrol 50 | Aluminum Chlorohydrate (50% solution) with an aluminum to chloride ratio of 2.0:1 |
| Reach 301L | Aluminum Octachlorohydrex Gly (45% solution) with low zirconium and a metals to chloride ratio of 1.15:1 |
| Rezal 67 | Aluminum Sesquichlorohydrate (50% solution) with an aluminum to chloride ratio of 1.65:1 |
| Reach AZO-956G | Economical Aluminum Zirconium Pentachlorohydrate (40% solution) with a metals to chloride ratio of 1.75:1 and no glycine |
| AZG-368/AZG-442 | Aluminum Zirconium Tetrochlorohydrate Gly (35%/45% solution) with a metals to chloride ratio of 1.4:1 |
| UltraZAG 88L | Enhanced Aluminum Zirconium Tetrachlorohydrex Gly (45% solution) with optimum zirconium and aluminum polymer distributions and a metals to chloride ratio of 1.15:1 |
